2017-07-14T18:53:53-07:00
Resource:GeneNetwork / WebQTL
GeneNetwork, WebQTL
curated
http://www.genenetwork.org/
A group of linked data sets and tools used to study complex networks of genes, molecules, and higher order gene function and phenotypes. It combines more than 25 years of legacy data generated by hundreds of scientists together with sequence data (SNPs) and massive transcriptome data sets (expression genetic or eQTL data sets). The quantitative trait locus (QTL) mapping module that is built into GN is optimized for fast on-line analysis of traits that are controlled by combinations of gene variants and environmental factors. GeneNetwork can be used to study humans, mice (BXD, AXB, LXS, etc.), rats (HXB), Drosophila, and plant species (barley and Arabidopsis). Most of these population data sets are linked with dense genetic maps (genotypes) that can be used to locate the genetic modifiers that cause differences in expression and phenotypes, including disease susceptibility.
Users are welcome to enter their own private data directly into GeneNetwork to exploit the full range of analytic tools and to map modulators in a powerful environment. This combination of data and fast analytic functions enable users to study relations between sequence variants, molecular networks, and function.
What can be done with GeneNetwork?
* QTL Mapping:
** Interval Mapping
** Simple interval mapping
** Composite interval mapping
** Pair-scan
* Correlation Analysis
** Correlation Matrix / Principal Components Analysis
** QTL Heatmaps
** Compare Correlates
** Network Graph
* Systems Genetics and Complex Trait Analysis
Source code is available and is written in Python, C, and JavaScript. The QTL Reaper module of GeneNetwork that is used by several mapping modules of GeneNetwork is also available.
Category:U01AA13499
Category:U24AA13513
Category:U01AA014425
Category:P20-DA 21131
Category:U01CA105417
Category:U24 RR021760
nif-0000-00380
Resource:GeneNetwork
2015-02-02T00:00:00
15043217, 15114364
Resource
www.genenetwork.org
GeneNetwork / WebQTL
GeneNetwork WebQTL
GeneNetwork and WebQTL
Resource
Resource:NIF Data Federation
Usedby
Synonym
National Center for Research Resources
National Cancer Institute
National Institute of Mental Health
National Institute on Drug Abuse
National Institute on Alcohol Abuse and Alcoholism
UT Center for Integrative and Translational Genomics
Supporting Agency
SuperCategory
Tomato
Soybean
Arabidopsis thaliana
Barley
Drosophila
Macaque
Human
Rat
Species
Resource:Monarch Initiative
RelatedTo
PMID
ModifiedDate
Label
Data sharing
Quantitative trait locus
Mapping
Data analysis service
Annotation
Microarray
Expression
MRNA
Environmental factor
Allelic variant
Behavior
Cancer susceptibility
Toxicity
Source code
Molecular neuroanatomy resource
Webgestalt
Transcript
Transcriptome
Trait
SNP
Sequence
Relational database
Phenotype
Network
Mouse
Gnf expression atlas
Genotype
Genomic region
Genome browser
Abi panther
Genome
Genetic correlation
Gene
Keywords
University of Tennessee Health Science Center; Tennessee; USA
Is part of
Id
Data repository
Database
Has role
Grant
File:GeneNetwork.png
ExampleImage
Definition
DefiningCitation
CurationStatus
The community can contribute to this resource
GNU General Public License
V3
GNU Affero General Public License
Acknowledgement requested
Public
Free
Availability
Abbrev