2010-11-16T12:25:13-08:00
Resource:Gene Expression Database
curated
http://www.informatics.jax.org/expression.shtml
<br />
GXD is a community resource for gene expression information from the laboratory mouse. GXD stores and integrates different types of expression data (RNA in situ hybridization; Immunohistochemistry; in situ reporter (knock in); RT-PCR; Northern and Western blots; and RNase and Nuclease S1 protection assays) and makes these data freely available in formats appropriate for comprehensive analysis.<br />
There is particular emphasis on endogenous gene expression during mouse development. More: GXD also maintains an index of the literature examining gene expression in the embryonic mouse. It is comprehensive and up-to-date, containing all pertinent journal articles from 1993 to the present and articles from major developmental journals from 1990 to the present.<br />
GXD stores primary data from different types of expression assays and by integrating these data, as data accumulate, GXD provides increasingly complete information about the expression profiles of transcripts and proteins in different mouse strains and mutants. GXD describes expression patterns using an extensive, hierarchically-structured dictionary of anatomical terms. In this way, expression results from assays with differing spatial resolution are recorded in a standardized and integrated manner and expression patterns can be queried at different levels of detail. The records are complemented with digitized images of the original expression data.<br />
The Anatomical Dictionary for Mouse Development has been developed by our Edinburgh colleagues, as part of the joint Mouse Gene Expression Information Resource project. GXD places the gene expression data in the larger biological context by establishing and maintaining interconnections with many other resources. Integration with MGD enables a combined analysis of genotype, sequence, expression, and phenotype data. Links to PubMed, Online Mendelian Inheritance in Man (OMIM), sequence databases, and databases from other species further enhance the utility of GXD. GXD includes 10,831 Genes studied in expression references; 8,661 Genes with expression assay results; 400,884 Expression assay results; 66,204 Expression images; 34,364 Expression assays; 1,325 Mouse mutants with expression data. GXD accepts both published and unpublished data.<br />
nif-0000-01253
Resource:Gene Expression Database
2010-09-21T00:00:00
GXD
Resource
Synonym
ModifiedDate
Label
Id
Data storage repository
Database
Has role
Definition
DefiningCitation
CurationStatus