2012-12-09T11:16:45-08:00
Resource:Clinical Trials Network (CTN) Data Share
CTN Data Share
Data for completed protocols will be available to the public approximately 18 months after completion of the study or after the acceptance of publication of the primary manuscript
whichever occurs first. Prior to downloading any study data
the user will be prompted to complete a registration agreement for data use.
curated
http://www.ctndatashare.org/
An electronic environment that allows data from completed clinical trials to be distributed to investigators in order to promote new research, encourage further analyses and disseminate information to the community. This site allows researchers to download de-identified data from completed CTN studies to conduct analyses that improve the quality of drug abuse treatment. Secondary analyses produced from data sharing multiply the scientific contribution of the original research.
To date, the efficacy of new treatments for drug addiction has been demonstrated primarily in specialized research settings, with somewhat restricted patient populations. To address this problem, the National Institute on Drug Abuse (NIDA) established the National Drug Abuse Treatment Clinical Trials Network (CTN). The CTN encourages investigators interested in drug abuse to use the CTNs clinical trials database to promote research.<br />
Effective data sharing includes communicating to the research community that data are available, providing sufficient descriptive information about the data, enforcing compliance to standard semantics and structure, rendering the data in a usable format, and making data accessible.<br />
Prior to de-identifying the data, all data files are converted from their native format to a modified Study Data Tabulation Model (SDTM) standard format. The SDTM is a content standard sponsored by the Clinical Data Interchange Standards Consortium (CDISC). This universal data format will be applied to each completed CTN trial's data. This will facilitate the pooling of shared data across completed studies.<br />
De-identified data are available for download in two formats: SAS (CDISC SDTM transport files) and ASCII (CSV files). Documentation regarding the data and corresponding study that generated the data are also available under each completed protocol page. This includes the annotated case report form (CRF); a define.xml file outlining the structure, variables and contents of each dataset; and SDTM mapping and de-identification rules.<br />
Prior to downloading any study data, the user will be prompted to complete a registration agreement for data use. Users will have to register a name, position, affiliation, and valid email in order to download data to accept their responsibility for using data in accordance with the CTN Data Share Agreement.
nif-0000-21981
Resource:Clinical Trials Network (CTN) Data Share
2012-11-08T00:00:00
Resource
NIDA Clinical Trials Data Share
CTN database
NIDA CTN Data Share
Resource:NIF Integrated Manually Extracted Annotation
Resource
Synonym
Supporting Agency
SuperCategory
Species
Resource:NIF Data Federation
RelatedTo
ModifiedDate
Label
Addiction
Drug
Drug addiction
Experimental protocol
Clinical trial
Human
Data sharing
Clinical
Drug Abuse
Keywords
National Institute on Drug Abuse
Is part of
Id
Data set
Has role
File:Ctn.jpg
ExampleImage
Definition
DefiningCitation
CurationStatus
Availability
Abbrev